Jan 15, 2026 · HK1 (Hexokinase 1) is a Protein Coding gene. Diseases associated with HK1 include Anemia, Congenital, Nonspherocytic Hemolytic, 5 and Neuropathy, Hereditary Motor …

Hexokinase I, also known as hexokinase A and HK1, is an enzyme that in humans is encoded by the HK1 gene on chromosome 10. Hexokinases phosphorylate glucose to produce glucose-6 …

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Jul 6, 2025 · Gene target information for HK1 - hexokinase 1 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

Jan 1, 2025 · Hexokinase 1 (HK1) encodes a ubiquitously expressed hexokinase, which is responsible for the first step of glycolysis, phosphorylation of glucose to glucose-6-phosphate.

Four different forms of hexokinase, designated type HK1, HK2 (601125), HK3 (142570), and HK4 (138079), encoded by different genes, are present in mammalian tissues.

Aug 8, 2022 · Hexokinase (HK)-1 mitochondrial-binding mechanisms and consequential physiological relevance remain unclear. Recently, De Jesus et al. studied myeloid cells with …

20 days Clinical & Interpretive Clinical Information Hexokinase (HK) is the first enzymatic step in. glycolysis, converting glucose to glucose 6-phosphate. Hexokinase deficiency (OMIM 235700) …

Feb 18, 2019 · HK1 is ubiquitously expressed but is abundant in the brain and is known as the ‘brain-type hexokinase’. HK1 consists of N-terminal regulatory and C-terminal catalytic domains.

Apr 7, 2022 · Our data indicate that HK1 mitochondrial binding alters glucose metabolism through regulation of GAPDH. Hexokinases (HKs) represent the first committed step in glucose …