Peer pressure often evokes unexpected behavior, and protein partners might do the same. The Methyl-CpG binding protein 2 (MeCP2) has long been considered a transcriptional repressor, given its ...

Leukemic disease can be linked to aberrant gene expression. This often is the result of molecular alterations in transcription factors that lead to their misrouting within the nucleus. The acute ...

ETS-domain transcription factors are found in all metazoan organisms and are characterised by the presence of a conserved DNA-binding domain (the ETS-domain). Other domains provide additional ...

Electrophoretic mobility shift assay, sometimes referred to as EMSA, is a sensitive method for investigating nucleic acid-protein binding. This is based on gel electrophoresis and is based on the ...

Gene expression can be regulated by various cellular processes with the aim to control the amount and nature of the expressed genes. Expression of genes can be controlled with the help of regulatory ...