Chromosome segregation during mitosis is coordinated by the mitotic spindle, which requires the joint activities of microtubules, microtubule-binding proteins and chromosomes. Although it has been ...
The nucleus is surrounded by the nuclear envelope (NE), which is formed by two juxtaposed membranes, termed the inner and outer nuclear membranes. A protein meshwork of intermediate filament proteins ...
Robert Blackwell, Christopher Edelmaier, Oliver Sweezy-Schindler, Adam Lamson, Zachary Gergely, Eileen O’Toole, Ammon Crapo, Loren Hough, J. Richard McIntosh ...
Every biology class learns about mitosis, which involves copying each of a cell's DNA-containing chromosomes, then separating them into two newly created cells. The act of chromosome separation is ...
Christopher J. Edelmaier, Adam R. Lamson, Zachary R. Gergely, Saad Ansari, Robert Blackwell, J. Richard McIntosh, Matthew A. Glaser, and Meredith D. Betterton (2020 ...
Mechanistic model for MTOC maturation in GV oocytes. The MTOC (grey) activates near the oocyte cortex, which requires recruitment of CKAP5 and TACC3. After activation, MTOC migrates to the nuclear ...
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