The natural RNAi mechanism can be directed by either short interfering RNA (siRNA) or microRNA (miRNA). 1 There are four key steps in the RNAi pathway. When miRNA acts as the guide for RNAi, only a ...
Drug development for the liver condition alpha-1 antitrypsin deficiency (AATD) has had its ups and downs lately, with Arrowhead Pharmaceuticals and Takeda posting phase 2 success and Vertex reporting ...
CAMBRIDGE, Mass. — Researchers at MIT and Alnylam Pharmaceuticals report this week that they have successfully used RNA interference to turn off multiple genes in the livers of mice, an advance that ...
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