Multiple fields of microbiology rely on techniques of microbial identification, such as in food microbiology for detecting contaminants, and in microbial ecology to characterize biodiversity. Image ...

Figure 1: Enzymatic cascade of the pyrosequencing reaction in the example of a bisulfite-treated template sequence, including a CpG position that is methylated on approximately 50% of all molecules.

The sequencing of DNA molecules started with the development of chemical cleavage method of Maxam-Gilbert during 1970s followed by di-deoxy chain termination method. However, the whole genome ...

Pyrosequencing as implemented by Roche's 454 is a technology that generates a large number of intermediate length DNA reads through a massively parallel sequencing-by-synthesis approach 1. The GS FLX ...

Roula Khalaf, Editor of the FT, selects her favourite stories in this weekly newsletter. Pal Nyren’s Eureka moment came in 1986 when he was cycling home from Cambridge university. “It is often when ...