Prototropic tautomerism in imidazole derivatives involves the rapid intramolecular transfer of a proton between the two nitrogen atoms of the imidazole ring, generating the N1-H and N3-H tautomeric ...
Quantum chemical investigations have become indispensable for elucidating the tautomeric equilibria of nucleobases, the prototropic isomers that underlie genetic fidelity, mutagenesis and ...