These cells are castration-resistant, meaning they continue to grow in the absence of testosterone and could explain how prostate tumors become resistant to hormone-related treatments. Prostate cancer ...

Researchers have characterized prostate cancer cell dynamics at a single-cell resolution across the timespan of the disease – from its beginning to the point of androgen independence, where the tumour ...

"Overall, our work highlights multiple epithelial and immune cell types that are crucial to prostate cancer initiation and progression, and sheds light on the interactions between specific cell ...