The authors studied the behavior of anhydrous lactose and the combination of anhydrous lactose and the combination of anhydrous lactose with microcrystalline cellulose on a pilot-scale roller ...

Several challenges may be presented when processing powder blends: the blend may be prone to segregation, the creation of agglomerates may influence homogeneity, or component powders may poorly flow ...

Using a novel automated microfilling system, the authors demonstrate that roller compaction followed by milling is a viable preprocessing technique for high-dose chemical-in-capsule dosage forms. The ...

Dry granulation is used in the pharmaceutical industry to improve powder flow by increasing their granular particle size. This is accomplished by using a roller press, which can be configured for ...

There are significant benefits to dry granulation, in terms of cost-reduction and processing, and it can be used with sensitive materials. However, there is little indication as to which process ...