Neddylation is a post-translational modification that controls the cell cycle and proliferation by conjugating the ubiquitin-like protein NEDD8 to specific targets. Here we report that glycyl-tRNA ...

A study reports for the first time on the importance of post-translational modification by neddylation in postnatal brain development. In particular, it is critical to synapse maturation and stability ...

Spanish researchers at CIC Biogune, the Cooperative Centre for Research into Biosciences and led by Dr. Maria Luz Martinez Chantar, have found a strong relationship between high levels of Hu antigen R ...

Professor Yi Sun's team at the Zhejiang University reported a functional compensatory effect between the Ube2m-Rbx1 and Ube2f-Sag axes of the neddylation-CRLs system in Treg cells, using conditional ...

Extracellular vesicles (EVs) are highly involved in the progression of diverse diseases. Therefore, targeting EV biogenesis is a potential strategy for the treatment of the related diseases, which ...