In 2015, a New Delhi -metallo-beta-lactamase (NDM) Escherichia coli bacteria was discovered in two Finnish dogs. An article recently published in the journal Eurosurveillance reveals that the dogs’ ...

New Delhi metallo-β-lactamase-1 exhibits a broad substrate profile for hydrolysis of the penicillin, cephalosporin and ‘last resort’ carbapenems, and thus confers bacterial resistance to nearly all ...

Based on amino acid sequence homology, β-lactamases are categorized into four classes, A, B, C, and D 4. Classes A, C, and D are referred as serine-β-lactamases (SBLs), as they utilize a Ser residue ...

Last night, prompted by Michael Coston's excellent primer on NDM-1 (one of a set of short courses he publishes periodically), I scrolled through the literature to see what had happened recently with ...

NDM-1 refers to a gene’s protein product that some bacteria make. A bacterial strain that carries NDM-1 will be resistant to even some of the strongest antibiotics. Few current antibiotics can combat ...

The most recent reports of superbugs in the professional and lay literature discuss NDM-1, which stands for New Delhi metallo-beta-lactamase 1 and actually refers not to a single bacterial species but ...

A concerning report from the CDC reveals a significant surge in drug-resistant "nightmare bacteria" infections across the United States, escalating nearly 70% between 2019 and 2023. The rise is ...

Antibiotic-resistant bugs have been around almost as long as antibiotics, and health officials have long warned about the looming danger of superstrains — bacteria that are impervious to all of our ...