New research offers clues about the biology of cells in the spinal cord that die off in amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. A team of researchers supported by the ...

An international team of investigators has discovered that an inorganic polyphosphate released by nerve cells known as astrocytes in people with amyotrophic lateral sclerosis (ALS) and frontotemporal ...

Pellecchia and colleagues hypothesize that interactions between motor neurons and astrocytes are responsible at least in part for the progression of motor neuron death in ALS patients. These ...

Results of a largescale collaborative project led by scientists at the Cedars-Sinai Medical Center, Los Angeles, and the University of California, Irvine (UCI), were published in the journal Neuron ...

A new genetic discovery adds weight to a theory that motor neuron degenerative diseases are caused by abnormal lipid (fat) processing pathways inside brain cells. This theory will help pave the way to ...

Researchers at the University of Bath have discovered how DNA damage caused by a faulty DNA protection and repair system can lead to neurodegenerative disorders such as motor neuron disease (MND).

A new genetic discovery adds weight to a theory that motor neurone degenerative diseases are caused by abnormal lipid (fat) processing pathways inside brain cells. This theory will help pave the way ...

A drug candidate found to protect nerve cells damaged by motor neuron disease (MND), could offer new hope to people living with the devastating condition. Subscribe to our newsletter for the latest ...

Motor neurons are some of the largest cells in the human body. In particular, upper neurons—extending from the cerebral cortex to the brain stem or spinal cord—average 60μm in diameter. 3,4 These ...

A drug typically used to treat enlarged prostates and high blood pressure has shown promise as a potential new therapy for motor neuron disease (MND) -- also known as amyotrophic lateral sclerosis ...