Determining true HER2 status in breast cancers with polysomy using alternative chromosome 17 reference genes: Implications for trastuzumab therapy. Background: Systemic chemo- and chemoradiation ...

A recent study led by Dr. Manel Esteller, Director of the Josep Carreras Institute, shows how DNA methylation profiling in a common type of blood cancer, myelodysplastic syndrome, predicts whether the ...

DNA methylation is a highly studied epigenetic modification that regulates genome function and plays key roles in development and disease 1. It is linked to a broad range of conditions, including ...

DNA methylation is an epigenetic modification crucial to normal development, with its dysregulation leading to various diseases including cancer. As interest in epigenomics grows, an innovative ...

Methylation analysis holds significant promise for clinical diagnostics, yet its use has been limited due to challenges posed by legacy technologies that undermine clinical applicability, such as ...

This article is based on a poster originally authored by Archana Bettadapur, Adam Barner, Melissa Netwal, Sanika Khare, Cam Jansen, and Dominic Skinner. Many epigenetics applications leverage the ...

CHICAGO (WLS) -- I'll never forget that day: December 21st, 2020. I was on the anchor desk delivering the morning news, while my husband was all alone at home having a massive seizure. Then, the ...

Researchers identified distinct patterns of epigenetic dysregulation in myeloproliferative neoplasms. Epigenetic changes in myeloproliferative neoplasms (MPNs) have been identified and characterized ...

The Genomics Core offers a variety of microarray analysis options for DNA and epigenetic studies. The Illumina BeadArray technology combined with the Illumina iScan Array Scanner allows for analysis ...

Researchers from Japan have now identified RABGGTB as a novel autism-linked gene during DNA methylation mapping in the dorsal raphe nuclei of the brain. Autism spectrum disorder (ASD) is a condition ...