Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.

Mutated variants of a particular ion channel cause difficult-to-treat epilepsy. A study published in the journal Nature now shows that a commonly used anesthetic drug, propofol, can restore the ...

When a scrappy team of scientists joined forces in the late 1990s, they sought to identify genetic mutations that could have an outsized impact on the treatment of human disease. At the time, that ...

A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function with a 'ball-and-chain' channel-plugging mechanism. The findings boost the ...