A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function with a “ball-and-chain” channel-plugging mechanism, according to investigators ...

A new study has rewritten the conventionally understood evolutionary history of certain ion channels -- proteins critical for electrical signaling in the nervous system. The study shows that the ...

A new understanding of how drugs are taken in by cells could impact the way drugs are administered to patients. In an Aug. 30 study published in Nature that details structural changes of the Transient ...

Scientists have identified the role of an ion channel that plays a key part in how cells break down and recycle components, a discovery that could open the door to new treatment strategies for ...

Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.

HHMI researchers discover a new ion channel that is found only in the tails of spermatozoa. An ion channel protein that plays a central role in sperm motility could be an enticing target for a new ...

Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge. Now, researchers have ...

Researchers decipher the function of an ion channel involved in cellular degradation processes and create new possibilities for Parkinson’s therapies.