The beating of a heart, the ability to learn and remember, and the movement of a sperm cell's tail all have at least one thing in common: They depend on the function of ion channels, the membrane ...

Researchers from Griffith University's National Center for Neuroimmunology and Emerging Diseases (NCNED) have made a discovery that could bring relief to those struggling with long COVID. In a ...

Mutated variants of a particular ion channel cause difficult-to-treat epilepsy. A study published in the journal Nature now shows that a commonly used anesthetic drug, propofol, can restore the ...

Neuroinflammation is now recognized as a central driver instead of being merely a consequence of many neurological diseases, including neurodegenerative ...

To transmit excitatory signals, nerve cells mostly use glutamate as a neurotransmitter. To detect these transmitter signals, ...

Microglia, the immune cells that protect the brain, are thought to maintain a healthy brain environment by removing unwanted substances through dynamic remodeling of the actin cytoskeleton, the cell's ...

Osteoarthritis (OA) is a highly prevalent joint disease that causes substantial disability, yet effective approaches to disease prevention or to the delay of OA progression are lacking. Emerging ...

Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge. Now, researchers at Weill ...

Osteoclasts are essential for bone resorption and interact with osteoblasts during bone remodeling. Ion channels and transporters located in the ruffled border or intracellular vesicles coordinate the ...

Researchers decipher the function of an ion channel involved in cellular degradation processes and create new possibilities for Parkinson’s therapies. Washbowls, bathtubs, and sinks are all fitted ...

A faulty ion channel function is a consistent biological feature of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), providing long-awaited validation for hundreds of thousands of ...

(Nanowerk Spotlight) Biological brains compute using ions, not electrons. Every signal between neurons depends on charged atoms passing through protein channels embedded in cell membranes, a system ...