Researchers have identified serine threonine kinase 10 as a key regulator of platelet function, haemostasis and ...

In a recent study published in the IUBMB journal, researchers assessed the association between platelet-activating factor (PAF) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ...

A new study created a score to identify patients with platelet hyperreactivity and risk of related, future cardiovascular disease. Platelets are circulating cell fragments known to clump up and form ...

Ado-trastuzumab emtansine (T-DM1) treatment results in grade 3-4 thrombocytopenia in 8%-13% of patients. Prior in vitro studies reported T-DM1 inhibition of megakaryocyte maturation as the cause of ...

Diminished platelet autophagy potentially contributes to thrombocytopenia in cirrhotic patients. H 2 S modulates platelet autophagy and functions possibly via the PDGFR-α/PI3K/Akt/mTOR signaling ...

Abstract and Introduction Review of Normal Platelet Physiology and Megakaryocytopoisis Qualitative Platelet Abnormalities Conclusion References Nitric oxide (NO) is another drug used in the neonatal ...

Managing drug dosage is critical to the overall success of pharmaceutical intervention, not only in the clinic but also in clinical trials. Inadequate dose management of certain drugs can have fatal ...

Platelets are circulating cell fragments known to clump up and form blood clots that stop bleeding in injured vessels. Cardiologists have long known that platelets can become "hyperreactive" to cause ...

The most common etiology of pseudothrombocytopenia is platelet clumping induced by EDTA, which is the anticoagulant present in the purple tube in which blood is collected for a CBC. This clumping is ...