Certain MS-driving immune cells express a protein marker called CD29, which helps these cells move into the brain and trigger inflammation.

Cholesterol drugs do more than move numbers. This deep dive into bempedoic acid explores a newly discovered PPARα mechanism, ...

Cellular death within the infarcted core occurs rapidly due to energy depletion, resulting in the release of DAMPs such as HMGB1, ATP, and HSPs. These DAMPs engage pattern recognition receptors, ...

A first-of-its-kind study has identified overactive inflammation and loss of critical protective mechanisms in the brain as potential contributors to suicide risk. The findings could lead to the use ...

Obesity associated with hypothalamic dysfunction was initially described in patients with craniopharyngioma. Hypothalamic obesity may also result from brain radiation, infection (eg, tuberculosis), ...

A research group led by Nagoya University Graduate School of Medicine in Japan has uncovered a potential mechanism linking maternal inflammation to delayed neurodevelopment in infants. The research ...

Inflammation can be good for the body, but too much can lead to a number of harmful health conditions. Look out for these ...

Periodontitis is a serious chronic inflammatory form of gum disease that affects millions worldwide. It can lead to tooth ...

Research shows a link between inflammation in the brain and migraine. Find out how inflammation might lead to pain and what ...

The understanding of fat has evolved in recent decades. Once regarded as nothing more than passive storage reservoirs for fat, adipocytes are now recognized as critical players in metabolic and ...