Lowering the dosage of a single gene from two copies to one copy in diploid yeast results in a heterozygote that is sensitized to any drug that acts on the product of this gene. This haploinsufficient ...

Your genes are made of DNA. This DNA provides instructions, which determines traits like your hair color and blood type. There are different versions of genes. Each ...

Structural and insertion-deletion (indel) variants have received considerable recent attention, partly because of their phenotypic consequences. Among these variants, the most common are small indels ...