Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

The process of steroidogenesis in Leydig cells is fundamental to male reproductive biology, involving the conversion of cholesterol into testosterone and other steroid hormones. This multifaceted ...

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts. RNA splicing is a cellular process ...

A new genome editing tool—minimal versatile genetic perturbation technology (mvGPT)—can achieve simultaneous and orthogonal gene editing and gene regulation in human cells. The coming together of ...

Researchers from the National University of Singapore (NUS) have revealed that diet and exercise can change gene regulation in the skeletal muscle of East Asians, highlighting the critical role of ...

Science X is a network of high quality websites with most complete and comprehensive daily coverage of the full sweep of ...

Sequence motifs and cleavage site specificity of DCL1 and other RNase III enzymes. (a) The GHR motifs define the DCL1 cleavage site. (b) Sequence motifs recognized by DCL1, Dicer, and Drosha, with ...

Our genes contain all the instructions our body needs to function, but their expression must be finely regulated to guarantee that each cell performs its role optimally. This is where DNA and RNA ...

Human health may be getting a big boost from the bits and bytes of computer science. In particular, artificial intelligence (AI) machine learning models are helping to unravel the mysteries of the ...

Some scientists believe that regulations on agricultural gene editing are too strict. However, a new study from the University of Adelaide emphasizes the need for clear guidelines to ensure these ...