In contrast to conventional organic synthesis, mechanochemistry does not use solvents that eventually become industrial wastes. Thus, mechanochemistry is environmentally friendly and enables us to ...

It’s a common enough scenario in many synthesis labs: you know what starting material you have, and you know what product you need but not quite what reaction conditions will get you there. Unless you ...

Chemists have developed a straightforward method to convert common chemicals like carboxylic acids, alcohols, and alkanes directly into valuable alkenes. Chemists from the National University of ...

This module teaches fundamentals of pericyclic reactions using examples of biocatalysis, biomimetic catalysis, and natural product total synthesis. After completion, students should be able to ...

Chemistry is all around us. From the widespread production of global food supplies to the metabolism that fuels the tiniest of microorganisms, everything in our surroundings is produced and controlled ...

A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl ...

It has been almost a quarter-century since K. Barry Sharpless, M.G. Finn, and Hartmuth C. Kolb published the paper that some refer to as the click manifesto. In it, the researchers presented a vision ...

Penn State researchers have uncovered a surprising twist in a foundational chemical reaction known as oxidative addition. Typically believed to involve transition metals donating electrons to organic ...