Scientists at UNIGE Faculty of Medicine show how genetic switches activate then deactivate the genes responsible for embryonic development. Their findings, published in Nature Communications, decipher ...

A research team showed that, contrary to current models, one early embryonic cell dominates lineages that will become the fetus. “They are not identical,” said Magdalena Zernicka-Goetz, a ...

Researchers at Tsinghua University have released a novel Python toolkit, scLT-kit, which automates the processing and analysis of single-cell lineage tracing data, delivering clear insights into how ...

Multicellular organisms, including humans, can be incredibly complex even though they start from one fertilized cell. The many cells that compose the tissues and organs in a body are derived from ...

The workflow of scLT-kit. Based on the time-series lineage tracing single-cell data (top left panel), scLT-kit calculates the barcoding fraction and clone sizes (top right panel, scLT-statistics ...

Chimpanzee naive pluripotent stem cells (PSCs) can now be grown in cellular cultures, reveals a recent study. They successfully created chimpanzee early embryo models, called 'blastoids,' and found ...