'Multi-zonal' liver organoids represent a significant step forward in developing lab-grown liver tissues. One reason why our livers excel at clearing waste from our blood system is that the organ ...

One reason why our livers excel at clearing waste from our blood system is that the organ functions according to three key "zones" that perform specific major tasks. So, if scientists hope to create ...

When mice with liver injuries received organoid tissue transplants, more of those receiving the multizonal versions (MZ organoids) survived longer than mice receiving either zone 3-only or Zone 1-only ...

Experts at Cincinnati Children's Report Breakthrough in Nature that Eventually Could Help Repair Patient Livers Injured by Disease CINCINNATI, April 16, 2025 /PRNewswire/ -- One reason why our livers ...

Scientists from Cincinnati Children’s Hospital Medical Center and their collaborators have used human stem cells to develop liver organoids that faithfully replicate key zones observed in human livers ...

In the short term, these multi-zonal liver organoids will help scientists shed new light on diseases including diabetes, drug-induced liver injury, alcohol-related liver disease, and viral hepatitis.