Prostate cancer is a prevalent disease that is characterized by a presumably long latency period and a moderate propensity to metastasize. Although a range of mechanisms have been implicated in ...

The discovery of gap junctions and their role in providing direct lines of communication between contacting cells dates back more than 50 years, and research into why healthy cells require this mode ...

Researchers have gained new knowledge of how drugs bind to connexin molecules. These molecules form channels that allow neighboring cells to send direct messages to one another. Dysfunctions of these ...

Connexins (Cxs) are a group of transmembrane proteins that assemble to form gap junction channels (GJCs). Each GJC is composed of two hemichannels or connexons, which in turn are constructed of six ...

Study reveals how drug molecules bind in channels between neighboring cells, changing intercellular communication. Researchers have gained new knowledge of how drugs bind to connexin molecules. These ...

Atrial fibrillation has always been the little sister to its ventricular counterpart — but during the past decade, it has captured our attention, mainly because it is so common. Atrial fibrillation ...

Neighboring cells exchange molecular information via channels that directly connect them. Disruption of this signaling system can lead to disorders ranging from hearing loss to heart disease Like ...