Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.

Researchers have unveiled a new mechanism for regulating mitochondrial function. The findings reveal the critical role played by the enzymatic activity of the lysine acetyltransferase MOF in ...

A new study offers a fresh perspective on the role of sodium in mitochondrial physiology and points the way to future research into the relationship between complex I disorders and a host of neuronal ...

Reduction in mitochondrial activity in multiple sclerosis contributes to Purkinje cell loss. Researchers at the University of California, Riverside (CA, USA) have demonstrated the role mitochondrial ...

Mitochondria are responsible for producing and providing energy to our bodies, especially in organs such as the heart, brain, and muscles, which require high-energy production. These organs ...

Healthy mitochondria existing as elongated network (left panels) become fragmented and functionally deficient upon MOF and COX17 genetic depletion (right panels). Immunofluorescence microscopic images ...