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A combination of differential expression and network connectivity analyses identifies a common set of RNA splicing and processing genes altered with age across human tissues ...

The cover of Aging-US Volume 17, Issue 12, features Figure 5 from the research paper, titled "A combination of differential expression and network connectivity analyses identifies a common set of RNA ...
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Combination of baicalin and gardenoside mitigates brain damage by lowering AQP-4 expression levels in rat model of cerebral ischemia/reperfusion

AC, allyl chloride; AQP-4, aquaporin-4; BBB, blood-brain barrier; BC, baicalin; GD, gardenoside; GLU, glucose; I/R, cerebral ischemia reperfusion; LA, lactic acid ...
GEN

AI Tool Uncovers Gene Combinations Underlying Genotype–Phenotype Relationships in Complex Traits

Northwestern University biophysicists have developed a new computational tool for identifying gene combinations underlying complex illnesses such as diabetes, cancer, and asthma. Unlike single-gene ...
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Modulation of enhancer of zeste homolog 2 (EZH2) pharmacodynamic (PD) markers and tumor gene expression by mevrometostat in combination with enzalutamide in patients with ...

Clinical outcomes of prompt versus deferred 177Lu-PSMA-617 initiation for metastatic castration-resistant prostate cancer (mCRPC) based on prior androgen receptor pathway inhibitor (ARPI) and taxane ...