Cell- and animal-based models of bone formation reveal novel mechanisms involved in the cartilage-to-bone phenotype transitions CHENGDU, SICHUAN, CHINA, March 20 ...

Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development ...

In vertebrates, the skeleton of different regions of the body arises from different precursor cells. Researchers have now discovered that these skeletal cells do not just differ in their developmental ...

The first 'blueprint' of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone ...

With funding from ARPA-H, three teams of researchers have regrown bone and cartilage, even entire knees, in animal studies. Human trials are not far off. By Gina Kolata Three years ago, a little-known ...

While aging is known to weaken bone repair, the underlying causes remain unclear. Researchers have now discovered that mitochondrial DNA structures called G-quadruplex accumulate in periosteal stem ...