Mutations in the microtubule-binding protein tau cause the protein to aggregate in neurodegenerative diseases such as some forms of frontotemporal dementia—but many conditions evince tau tangles in ...

Hereditary axonal peripheral neuropathies comprise a genetically heterogeneous group of disorders that are clinically subsumed under the name of Charcot–Marie–Tooth (CMT) disease type 2 (CMT2).

Reactivating damaged motoneurons Thomas Herrmannsdörfer (left) and Richard Funk are investigating the therapeutic effect of magnetic fields on impaired motoneurons. (Courtesy: HZDR/Amac Garbe) ...

Seeking students to contribute to research exploring motor-disease protein complexes and their role in intracellular transport, as they relate to disease initiation and the aging process, and the ...

Early in the course of Alzheimer disease, blockages in axonal traffic lead to sick axons swollen with the jumbled pile-up of traffic components. The blockages precede overt amyloid pathology in AD ...