Scientists have uncovered a surprising secret hidden inside fat cells that could reshape how we think about obesity and metabolic disease. A protein called HSL, long believed to simply release stored ...

HSL contributes to the mobilization of fats stored in the lipid droplet. In the nucleus, HSL ensures the proper functioning of the adipocyte. Our fat cells, called adipocytes, do more than just store ...

Scientists have uncovered a surprising second role for a protein long believed to simply burn fat. The discovery reveals that ...

Uncovering the mystery of why individuals born with mutations in the gene that encodes HSL—the cytosolic enzyme that releases energy from fat—lose fat instead of gaining it, Dominique Langin, PhD, ...

Workflow to perform snRNA-seq of different WAT depots. The nuclei were derived from subcutaneous (S), epididymal (E), mesenteric (M), peri-nephritic (N), and peri-heart (H) adipose depots, which were ...

Our fat cells, called adipocytes, do more than just store extra weight. They play a key role in managing the body's energy. Adipocytes accumulate fat in the form of lipid droplets that the body can ...

Fat is in the spotlight again, but the latest news isn’t about how to lose it or why it’s bad for you. Rather, scientists have discovered new insights into how fat cells self-regulate — surprising the ...